Two sample MR report
ZNF506_Alveolar Macrophages against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 5 | -0.0171033 | 0.1435570 | 0.9126953 |
| Weighted median | 5 | -0.0251078 | 0.0088101 | 0.0043736 |
| Inverse variance weighted | 5 | -0.0210451 | 0.0068014 | 0.0019733 |
| Simple mode | 5 | -0.0277264 | 0.0124311 | 0.0895716 |
| Weighted mode | 5 | -0.0277264 | 0.0124841 | 0.0905186 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 1.728312 | 3 | 0.6306578 |
| Inverse variance weighted | 1.729068 | 4 | 0.7854309 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.004244 | 0.1543904 | 0.9797961 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 5.73e-05 | 0 | TRUE | 0.4758414 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
